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In a clinical study performed in a laboratory classroom, Quillivant XR was found effective at reducing the symptoms of ADHD in children ages 6-12 years at all measured times (45 minutes, 2, 4 [primary endpoint], 8, 10, and 12 hours after taking) compared to a sugar pill.

In a clinical study, QuilliChew ER improved attention and behavior compared to a sugar pill at 45 minutes, 2, 4, and 8 hours after taking.