Common Questions about Quillivant XR

Product Information

What is Quillivant XR® (methylphenidate HCl)?

Quillivant XR is used for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). It is a liquid medicine that is taken by mouth once in the morning, and should be used as part of a total treatment program for ADHD that may include counseling or other therapies.


Back to Top

What does the XR stand for in Quillivant XR?

The XR stands for “extended release.”


Back to Top

Why is Quillivant XR considered an extended-release medicine?

Quillivant XR is a long-lasting medicine. This means that Quillivant XR only needs to be taken once each day in the morning, and the medicine is released into the body throughout the day.


Back to Top

How were the effects of Quillivant XR measured?

The effectiveness of Quillivant XR was assessed in a laboratory classroom study. At the end of each week, teachers and raters used a rating scale (SKAMP) to evaluate the efficacy of Quillivant XR on attention and behavior in children with ADHD ages 6-12 years. Quillivant XR was demonstrated to start working in 45 minutes and keep working for 12 hours after taking.


Back to Top

What does Quillivant XR taste like?

Quillivant XR is fruit-flavored.


Back to Top

How do I store Quillivant XR?

Store Quillivant XR in a safe place at 59°F to 86°F (15°C to 30°C). Keep Quillivant XR and all medicines out of the reach of children.


Back to Top

How is Quillivant XR supplied?

Quillivant XR comes as a powder that your pharmacist will mix for you into a liquid. You will be given 1 bottle (containing the liquid form of Quillivant XR), 1 oral dosing dispenser, and 1 bottle adapter.

Please refer to the Instructions for Use for a full description of each item.


Back to Top

How to Take Quillivant XR

How should Quillivant XR be taken?

  • Take Quillivant XR exactly as prescribed. Your healthcare professional may adjust the dose until it is right for you or your child
  • Take Quillivant XR once each day in the morning. Quillivant XR is an extended-release suspension. It releases medicine into your body throughout the day
  • Quillivant XR should be used with the oral dosing dispenser provided with the product. If the oral dosing dispenser is missing or not provided, please contact your pharmacist for a replacement
  • Quillivant XR can be taken with or without food. Taking Quillivant XR with food may shorten the time it takes for the medicine to start working
  • From time to time, your healthcare professional may stop Quillivant XR treatment for a while to check ADHD symptoms
  • Your healthcare professional may do regular checks of the blood, heart, and blood pressure while taking Quillivant XR
  • Children should have their height and weight checked often while taking Quillivant XR. Quillivant XR treatment may be stopped if a problem is found during these check-ups
  • In case of poisoning, call your poison control center at 1-800-222-1222 right away, or go to the nearest hospital emergency room

Back to Top

How often do you take Quillivant XR?

Quillivant XR is taken once each day in the morning.


Back to Top

Duration Information

When does Quillivant XR start working?

Quillivant XR was demonstrated to start working 45 minutes after taking.


Back to Top

How long do the effects of Quillivant XR last?

Quillivant XR works in 45 minutes and keeps working for 12 hours after taking. That means that when taken at 7 AM, Quillivant XR may be effective through homework time.


Back to Top

Safety Information

Can Quillivant XR be habit-forming?

Quillivant XR is a federally controlled substance (CII) because it can be abused or lead to dependence. Keep Quillivant XR in a safe place to prevent misuse and abuse. Selling or giving away Quillivant XR may harm others, and is against the law.

Tell your healthcare professional if you or your child have (or have a family history of) ever abused or been dependent on alcohol, prescription medicines, or street drugs.


Back to Top

What is the most important information I should know about Quillivant XR?

The following have been reported with the use of methylphenidate hydrochloride and other stimulant medicines.

Heart-related problems

  • Sudden death in patients who have heart problems or heart defects
  • Stroke and heart attack in adults
  • Increased blood pressure and heart rate

Tell your healthcare professional if you or your child have any heart problems, heart defects, high blood pressure, or a family history of these problems.

Your healthcare professional should check you or your child carefully for heart problems before starting Quillivant XR.

Your healthcare professional should check your or your child's blood pressure and heart rate regularly during treatment with Quillivant XR.

Call your healthcare professional right away if you or your child have any signs of heart problems such as chest pain, shortness of breath, or fainting while taking Quillivant XR.

 

Mental (Psychiatric) problems

All Patients

  • New or worse behavior and thought problems
  • New or worse bipolar illness

Children and Teenagers

  • New psychotic symptoms (such as hearing voices, believing things that are not true, are suspicious) or new manic symptoms

Tell your healthcare professional about any mental problems you or your child have, or about a family history of suicide, bipolar illness, or depression.

Call your healthcare professional right away if you or your child have any new or worsening mental symptoms or problems while taking Quillivant XR, especially seeing or hearing things that are not real, believing things that are not real, or are suspicious.

 

Circulation problems in fingers and toes (peripheral vasculopathy, including Raynaud’s phenomenon)

  • Fingers or toes may feel numb, cool, painful
  • Fingers or toes may change color from pale, to blue, to red

Tell your healthcare professional if you have or your child has numbness, pain, skin color change, or sensitivity to temperature in the fingers or toes.

Call your healthcare professional right away if you have or your child has any signs of unexplained wounds appearing on fingers or toes while taking Quillivant XR.


Back to Top

Who should not take Quillivant XR?

Quillivant XR should not be taken if you or your child:

  • Are allergic to methylphenidate hydrochloride, or any of the ingredients in Quillivant XR. See the end of the Medication Guide for a complete list of ingredients in Quillivant XR
  • Are taking or have taken within the past 14 days an antidepression medicine called a monoamine oxidase inhibitor or MAOI

Back to Top

Are there any health conditions I should tell my healthcare professional about?

Quillivant XR may not be right for you or your child. Before starting Quillivant XR tell your or your child's healthcare professional about all health conditions (or a family history of) including:

  • Heart problems, heart defects, high blood pressure
  • Mental problems including psychosis, mania, bipolar illness, or depression
  • Circulation problems in fingers and toes
  • Are pregnant or plan to become pregnant. It is not known if Quillivant XR will harm your unborn baby. Talk to your healthcare professional if you are pregnant or plan to become pregnant
  • Are breastfeeding or plan to breast feed. Quillivant XR passes into your breast milk. You and your healthcare professional should decide if you will take Quillivant XR or breast feed

Back to Top

What medicines should my healthcare professional know I’m taking before starting on Quillivant XR?

Tell your healthcare professional about all of the medicines that you or your child takes including prescription and nonprescription medicines, vitamins, and herbal supplements. Quillivant XR and some medicines may interact with each other and cause serious side effects. Sometimes the doses of other medicines will need to be adjusted while taking Quillivant XR.

Your healthcare professional will decide whether Quillivant XR can be taken with other medicines.

Especially tell your healthcare professional if you or your child takes:

  • Antidepression medicines including MAOIs
  • Cold or allergy medicines that contain decongestants
  • Know the medicines that you or your child takes. Keep a list of your medicines with you to show your healthcare professional and pharmacist

Do not start any new medicine while taking Quillivant XR without talking to your healthcare professional first.


Back to Top